XenoWorks® is a modular microinjection system designed to meet a wide variety of application needs. Our experience with precision motor control has culminated in this state of the art system.

The XenoWorks Micromanipulator uses a classic inverted joystick design for excellent ergonomics, intuitively linking the user with the micropipette. Combined with our smooth, responsive stepper-motor drives, the XenoWorks Manipulator provides exceptional mechanical stability, sensitivity, and range of movement.

The XenoWorks Digital Microinjector was designed for precision manipulation of cells via an easy-to-use interface. The Digital Microinjector employs two pressure ports, one for holding suspended cells, and a second channel is available for both high-pressure injection and gentle positive / negative pressure for transfer of embryonic stem cells. Both injection duration and pressure are easily selectable using rotary knobs on the remote interface. The built-in compressor removes the need for an external pressure supply.

The XenoWorks family also includes the Analog Microinjector for simple cell holding and transfer applications, which incorporates the same smooth response and ergonomic design of our other XenoWorks products.

APPLICATIONS
• Pronuclear microinjection of DNA into mouse zygote
• Embryonic stem cell transfer into blastocysts
• Somatic cell nuclear transfer (ES cell)
• Intracytoplasmic sperm injection (ICSI)
• Piezo-assisted sperm-mediated transgenesis Nuclear transfer (NT)
• Adherent cell microinjection
• Drosophila injection
• C. elegans injection
• Zebra fish injection
• Contact Sutter for suitability of XenoWorks for applications not listed here

FEATURES
• Exceptionally smooth and responsive micropipette movement
• Six movement sensitivities
• Height- and tension-adjustable inverted joystick for optimal ergonomics
• Up to 25 mm of movement in three axes
• User defined “Work” and Z-axis limit

DIGITAL MICROINJECTOR
• Independent “hold” and inject/transfer channels
• Femtoliter resolution injection
• Up to 5,600 hPa of injection pressure
• Remote keypad with rotary controls and high-visibility LED displays

ANALOG MICROINJECTOR
• Coarse and fine control
• Use with a variety of hydraulic fluids, including oil, air and water
• Interchangeable syringes allow sensitivity to be modified